SCHEDULED80% CONFIDENCETVmaze's[1][2] forward schedule gives 2026-09-20 as the announced premiere on FOX.
- Start
- Sep 21, 202675% CONFIDENCEfrom the source
Best Medicine Season 2 Premieres
In Best Medicine a brilliant surgeon leaves Boston to become a small-town doctor where he spent childhood summers. Despite his medical skills, his rude manner alienates locals as he battles hidden phobias and struggles with personal connections. The premiere, "Be Careful What You Fish For": While Martin continues to struggle with his blood phobia, a mermaid washes ashore in Port Wenn to the amazement of everyone in town. Meanwhile, Judith, a well-meaning townsperson creates havoc while on prescribed oxygen, Louisa continues to see Martin's girlfriend Eden for medical guidance and Greg and George's success from the seas urchin boom take its toll on the both of them. Season 2 starts on FOX.
- Best Medicine season 2 opens with 2x01 "Be Careful What You Fish For", airdate Sunday Sep 20, 2026 at 20:00 on FOX, running 60 minutes, with a trailer listed and a rating line reading "(waiting for more votes)"[1][2]
- The show page lists the series schedule as Tuesdays at 20:00 but gives this episode's day as Sunday, Sep 20, 2026 - the premiere is off its usual night[2]
- Synopsis: "While Martin continues to struggle with his blood phobia, a mermaid washes ashore in Port Wenn to the amazement of everyone in town. Meanwhile, Judith, a well-meaning townsperson creates havoc while on prescribed oxygen, Louisa continues to see Martin's girlfriend Eden for medical guidance and Greg and George's success from the seas urchin boom take its toll on the both of them"[1][2]
- Premise: "In Best Medicine a brilliant surgeon leaves Boston to become a small-town doctor where he spent childhood summers. Despite his medical skills, his rude manner alienates locals as he battles hidden phobias and struggles with personal connections"[2]
- Andrea Martin guests as Judith; the returning cast is Josh Charles as Dr. Martin Best, Abigail Spencer as Louisa Gavin, Josh Segarra as Sheriff Mark Mylow, Annie Potts as Aunt Sarah, Cree as Elaine Denton, Jason Veasey as George Brady and Stephen Spinella as Greg Garrison[1][2]
- Status is "Running; returning September 2026", a scripted Drama/Comedy/Medical series on FOX (2026 - now) developed by Liz Tuccillo, with 14 episodes ordered and a TVmaze rating of 6.1 from 38 votes[2]
- Season 1 ended on Apr 7, 2026 with 1x13 "Norway No How", after 1x12 "A Tale of Two Sister Cities" on Mar 31 and 1x11 "Mind Your Own Buboes" on Mar 24[2]
- It is an adaptation of ITV's Doc Martin, listed as its parent show, and is known as "Dr. Best" in Hungary; linked headlines are "'Best Medicine' Renewed for Season 2 at Fox" and "FOX Commissions 'Best Medicine' Based on ITV's 'Doc Martin'"[2]
References 280% CONFIDENCE
The first entry is always the pin's source. Overall confidence is a weighted average of how firmly each reference supports the start and end times used above; a reference counts half as much for every 180 days older than the newest.
- [1]75%tvmaze.com/episodes/3673496/best-medicine-2x01-be-careful-what-you-fish-fortvmaze.com· Posted Sep 20, 2026· Starts Sep 21, 2026 ✓· 50% of score
TVmaze's[2] forward schedule gives 2026-09-20 as the announced premiere on FOX.
- [2]85%Best Medicine - TVmazetvmaze.com· Added Sep 20, 2026· 50% of score
TVmaze's[1] page for the show, giving its run, status and season list; the premiere episode's own page is the pin's source.
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