Chronopin: upcoming release dates, events and other important dates

Nestlé aims to finish cutting about 16,000 jobs and reach CHF 3.0 billion of Fuel for Growth cost savings by the end of 2027. By mid-2026 it reported CHF 1.7 billion of savings delivered.

The Global Polio Eradication Initiative's extended strategy sets certification of wild poliovirus type 1 eradication by the end of 2027, with transmission in Afghanistan and Pakistan meant to stop first. Both countries still report cases.

The 33,000-seat domed ballpark, designed by Bjarke Ingels Group and HNTB around one of the largest cable-glass windows in North America, is rising on a corner of the 35-acre site of the Tropicana Las Vegas, which was imploded in October 2024. Construction broke ground in June 2025 on a roughly $2 billion build that brings Major League Baseball to the Strip.

Flight tests of the UK’s crewed sixth-generation demonstrator are due to start from early 2028, after power-on in mid-2027. More than 11,500 parts – about 90% of the aircraft’s weight – have been designed and released, with final assembly under way in Lancashire.

Greatest eclipse falls at 15:07:46 UT on 2028-01-26, where the annular phase lasts 10 minutes 27 seconds on a path 323.0 km wide; the longest annularity anywhere on the track is 10m30.6s. The path of annularity crosses Ecuador, Peru, Brazil, Suriname, Spain and Portugal, and a partial eclipse is visible from eastern North America, C. & South America, western Europe and northwestern Africa.

The NFL championship game for the 2027 season is played at Mercedes-Benz Stadium in Atlanta, the city's fourth Super Bowl and the second at this venue after Super Bowl LIII in 2019. CBS has the national broadcast.

Novo Nordisk's phase 3 trial of Cagrisema in obesity reaches primary completion, the point at which the last participant's primary outcome is measured. The trial enrolled 2,500 participants. This clinical study is testing how the study medicine CagriSema helps people living with obesity, with or without type 2 diabetes (T2D), lose weight. The purpose of the study is to find out how safe and effective CagriSema is for body weight loss in these participants. Participants will receive either CagriSema or semaglutide, and which treatment participants receive is decided by chance. CagriSema is a new study medicine being tested, while semaglutide is a medicine that doctors can already prescribe.

Sanofi's phase 3 trial of MenQuadfi in meningococcal infection reaches primary completion, the point at which the last participant's primary outcome is measured. The trial enrolled 4,568 participants. The purpose of this study is to describe the safety and immunogenicity of MenACYW conjugate vaccine compared with locally-licensed meningococcal vaccines in healthy infants and toddlers in China. Study details include: * Study duration (including 6-month safety follow-up after the last dose): * Cohort I (Groups 1 and 2): approximately 211 or 271 days (approximately 7 or 9 months) * Cohort II (Groups 3 and 4): up to 18 months * Cohort III (Groups 5 and 6): up to 21 months * Cohort III (Group 7): approximately 16 months * Vaccination Visits Period: * Cohort I (Groups 1 and 2): a 2-dose vaccination at V01 (D01) and V02 (D31) or V03 (D91). Two blood samples are collected pre-vaccination (D01) and 30 days post the 2nd dose of vaccination (D61 or D121).

After more than 80 years of proposals, Bogotá's first metro line, an elevated 24km driverless railway, is targeted to carry its first passengers in 2028.

The 385 m, 62-storey centrepiece of the Tokyo Torch district beside Tokyo Station holds offices, more than 100 shops, an events hall for 2,000 people and the first luxury rental flats in the Otemachi-Marunouchi-Yurakucho district. Construction started in September 2023.

EU member states must have mandatory extended-producer-responsibility schemes for textiles and footwear running by 16 April 2028, 30 months after the revised Waste Framework Directive entered into force. The schemes make clothing and footwear makers fund the collection, sorting and recycling of textile waste.

The UAW's contracts with General Motors, Ford and Stellantis run out on 30 April 2028 - a date the union chose so members could strike on May Day.

A 700,000-square-foot building joined to the George R. Brown Convention Center, holding two exhibition halls, an atrium hall and the largest ballroom in Texas, plus a 100,000-square-foot pedestrian plaza linking it to the Toyota Center. Houston First financed this first phase of its $2 billion convention district transformation with about $1.38 billion of hotel occupancy tax and special revenue bonds.

Boehringer Ingelheim's phase 3 trial of Vicadrostat in heart failure reaches primary completion, the point at which the last participant's primary outcome is measured. The trial enrolled 6,000 participants. This study is open to adults aged 18 or above legal age with heart failure. People can join the study if they have heart failure symptoms and a left ventricular ejection fraction (LVEF) of 40% or more. The purpose of this study is to find out whether vicadrostat (BI 690517) in combination with empagliflozin helps people with heart failure. Participants are put into 2 groups by chance. Every participant has an equal chance of being in each group. The groups are: * Vicadrostat/empagliflozin group: participants take vicadrostat/empagliflozin as tablets once a day. * Placebo/empagliflozin group: participants take placebo/empagliflozin as tablets once a day. Participants can stay in the study as long as they benefit from treatment and can tolerate it. During this time, they visit their doctors regularly. The doctors regularly check participants' health and take note of any unwanted effects.

The inbound half of LAX's 4.4-mile roadway rebuild, which separates airport traffic from Sepulveda Boulevard and neighbourhood streets, is due in May 2028, two months before the Games.

Victoria's largest road project, burying the missing link in Melbourne's ring road in twin three-lane tunnels. Estimated date.

An elevated 24 km driverless line, the first metro for a capital that has debated building one since the 1940s. Estimated date.

The United Kingdom and Ireland co-host the European Championship across nine stadiums. Estimated date.

GSK's phase 3 trial of MRNA Seasonal Flu Vaccine in influenza, human reaches primary completion, the point at which the last participant's primary outcome is measured. The trial enrolled 54,000 participants. This study will compare an investigational mRNA flu vaccine with a licensed flu vaccine in adults 65 years of age and older. Participants will receive one injection and will be followed during the flu season. The study will measure prevention of laboratory-confirmed flu illness, side effects, and immune responses.

Amgen's phase 3 trial of Maridebart Cafraglutide in heart failure with preserved ejection fraction reaches primary completion, the point at which the last participant's primary outcome is measured. The trial enrolled 5,056 participants. This trial will examine if maridebart cafraglutide as an adjunct to standard of care will lead to a reduction in heart failure (HF) events such as HF hospitalizations and urgent HF visits, cardiovascular (CV) deaths and improvement in HF symptoms in participants with HF with preserved ejection fraction (HFpEF) and HF with mildly reduced ejection fraction (HFmrEF) who are obese. This is a phase 3, global, multicenter, 2-part trial with a double-blind period and an open-label extension (OLE). The trial is event-driven, and Part 1 will conclude when approximately 850 primary endpoint events have occurred.

Amgen's phase 3 trial of Maridebart Cafraglutide in atherosclerotic cardiovascular disease reaches primary completion, the point at which the last participant's primary outcome is measured. The trial enrolled 12,800 participants. The primary objective of this trial is to demonstrate that maridebart cafraglutide is superior to placebo when given as an adjunct to standard of care with respect to reducing cardiovascular (CV) morbidity and mortality.